1.PRODUCT DESCRIPTION

Dextranase (EC 3.2.1.11) is primarily produced through microbial fermentation, including strains of *Streptomyces* (e.g., *Streptomyces mutans*), *Bacillus*, and fungal species (e.g., *Aspergillus niger*). Industrial production utilizes submerged fermentation with optimized culture media to achieve high enzyme activity.

Appearance: Yellow to brown solid powder or amber to brown liquid.

  Application Industries

**Food & Beverage ：Beer brewing, juice clarification, baking, and sugar processing.

**Pharmaceuticals & Healthcare： Dental care, drug delivery systems, and therapeutic agents for dextran-related disorders.

**Agriculture & Feed： Feed additives for improving nutrient digestion.

**Industrial Manufacturing： Paper pulping, microbial fermentation, and wastewater treatment.

**Research & Biotechnology： Biochemical research, dextran structure analysis, and enzyme engineering.

2 .‌ PRODUCT ADVANTAGE

2.1 Functions and Uses 

√ Degrades Dextran ：Specifically hydrolyzes α-1,6-glycosidic bonds in dextran, converting insoluble/high-viscosity dextran into soluble oligosaccharides or monosaccharides.

√Improves Process Efficiency** – Enhances filtration speed in beer and juice production, reduces viscosity in fermentation broths, and optimizes paper pulp drainage.

√Prevents Dental Caries** – Breaks down dextran in oral biofilms to inhibit plaque formation.

√Enhances Feed Utilization** – Degrades anti-nutritional dextran in feed to improve animal digestion and growth performance.

2.2  Action Effects

**In Food Industry** – Beer: Reduces wort viscosity by ≥30%, improves filtration rate by 50%, and enhances clarity. – Juice: Increases juice yield by 8-12% and reduces turbidity by ≥40%.

**In Pharmaceuticals** – Oral care: Decreases plaque formation by 60-70% in vitro.

**In Feed Additives** – Improves feed conversion ratio by 5-8% in poultry and swine.

**In Industrial Applications** – Paper pulp: Reduces drainage time by 20-30% and improves paper strength.

3. TECHNICAL PARAMETERS/MECHANISM

Catalytic Mechanism** Dextranase recognizes the α-1,6-glycosidic linkages in dextran molecules and catalyzes their hydrolysis via a retaining or inverting mechanism, depending on the enzyme source. Conserved amino acid residues (e.g., Asp, Glu) in the active site form a catalytic dyad to facilitate bond cleavage.

3.1  Technical Parameters  **Optimal Conditions** 

Temperature: 40-60°C (varies by strain, )           pH: 4.5-7.5

3.2  Dosage and Usage 

**Food Processing** 0.1-0.5 kg/ton of substrate (adjusted based on dextran content and enzyme activity).

**Feed Additives** 50-100 g/ton of feed, mixed uniformly during formulation.

The  dosage has to be optimized based on each application, the raw material specifications, product expectation and processing parameters. It is better to begin the test with the convenient volume.

4.PACKAGE AND STORAGE

• Package：25kg/drum.
• Storage：Keep sealed in a dry and cool place and avoid direct sunlight. Slight sedimentation is acceptable since it will not impact performance of the product.
• Shelf life: 12 months in a dry and cool place.